2024

Yang, J.*#, Wang, C.*, Fu, D.*, Ho, L.-L., Galani, K., Chen, L., Frederick, D.T., He, L., Huang, A.Y., Robitschek, E.J., Yadav, S.K., Deng, W., Tacke, R., Burke, K.P., Sharova, T., Rai, K., Liu, D., Boland, G.M.#, Kellis, M.#, 2024. Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma. https://doi.org/10.1101/2024.06.20.599945

Babu, S., Chen, J., Robitschek, E., Baron, C.S., McConnell, A., Wu, C., Dedeilia, A., Sade-Feldman, M., Modhurima, R., Manos, M.P., Chen, K.Y., Cox, A.M., Ludwig, C.G., Yang, J., Kellis, M., Buchbinder, E.I., Hacohen, N., Boland, G.M., Abraham, B.J., Liu, D., Zon, L.I., Insco, M.L., 2024. Specific oncogene activation of the cell of origin in mucosal melanoma. bioRxiv 2024.04.22.590595. https://doi.org/10.1101/2024.04.22.590595

Revach, O.-Y., Cicerchia, A.M., Shorer, O., Petrova, B., Anderson, S., Park, J., Chen, L., Mehta, A., Wright, S.J., McNamee, N., Tal-Mason, A., Cattaneo, G., Tiwari, P., Xie, H., Sweere, J.M., Cheng, L.-C., Sigal, N., Enrico, E., Miljkovic, M., Evans, S.A., Nguyen, N., Whidden, M.E., Srinivasan, R., Spitzer, M.H., Sun, Y., Sharova, T., Lawless, A.R., Michaud, W.A., Rasmussen, M.Q., Fang, J., Palin, C.A., Chen, F., Wang, X., Ferrone, C.R., Lawrence, D.P., Sullivan, R.J., Liu, D., Sachdeva, U.M., Sen, D.R., Flaherty, K.T., Manguso, R.T., Bod, L., Kellis, M., Boland, G.M., Yizhak, K., Yang, J., Kanarek, N., Sade-Feldman, M., Hacohen, N., Jenkins, R.W., 2024. Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy. bioRxiv 2024.02.12.579184. https://doi.org/10.1101/2024.02.12.579184

Pujadas Liwag, E.M., Wei, X., Acosta, N., Carter, L.M., Yang, J., Almassalha, L.M., Jain, S., Daneshkhah, A., Rao, S.S.P., Seker-Polat, F., MacQuarrie, K.L., Ibarra, J., Agrawal, V., Aiden, E.L., Kanemaki, M.T., Backman, V., Adli, M., 2024. Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism. Genome Biol 25, 77. https://doi.org/10.1186/s13059-024-03212-y

2023

[Review] Wendi Liu*, Anusha Puri*, Doris Fu*, Lee Chen, Cassia Wang, Manolis Kellis, Jiekun Yang#, Dissecting the tumor microenvironment in response to immune checkpoint inhibitors via single-cell and spatial transcriptomics, Clinical & Experimental Metastasis (2023). https://doi.org/10.1007/s10585-023-10246-2

[Review] Cassia Wang*, Lee Chen*, Doris Fu, Wendi Liu, Anusha Puri, Manolis Kellis, Jiekun Yang#, Antigen presenting cells in cancer immunity and mediation of immune checkpoint blockade, Clinical & Experimental Metastasis (2024). https://doi.org/10.1007/s10585-023-10257-z

2022

Jiekun Yang*, Maria Vamvini*, Pasquale Nigro*, Li-Lun Ho, Kyriakitsa Galani, Marcus Alvarez, Yosuke Tanigawa, Ashley Renfro, Nicholas P. Carbone, Markku Laakso, Leandro Z. Agudelo, Päivi Pajukanta, Michael F. Hirshman, Roeland J.W. Middelbeek, Kevin Grove, Laurie J. Goodyear#, Manolis Kellis#, Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cellsCell Metabolism, Volume 34, Issue 10, 2022, Pages 1578-1593.e6, ISSN 1550-4131,
https://doi.org/10.1016/j.cmet.2022.09.004(https://www.sciencedirect.com/science/article/pii/S1550413122003941)

* denotes equal contribution; # denotes correspondence